Preheat the oven to 350°F (180°C) or air fryer to 375°F
Make the ranch dressing: Place the cottage cheese, mayonnaise, buttermilk or milk, parsley, chives, dill, lemon juice, garlic powder, onion powder, salt, and pepper in a food processor or high-speed blender. Process for about 1 minute and 30 seconds, or until combined and smooth. To keep a thick consistency avoid over blending. Set aside.
Place the tortilla on a parchment paper-lined baking sheet. Spread the marinara evenly over the tortilla, then add the shredded cheese and pepperoni. Bake in the preheated oven or air fryer for about 5 minutes, or until the cheese is melted. Remove from the oven, and let cool for a few minutes.
Meanwhile, in a medium bowl, toss together the lettuce, tomatoes, and 2 tablespoons of the ranch dressing. Add more dressing to taste. (Store the remaining ranch dressing in an airtight container in the refrigerator for up to 1 week.)
Spoon the ranch-dressed salad down the center of the warm pizza-topped tortilla. Gently fold in the sides, then roll it up, tucking the filling in. Slice in half, and serve while it’s still warm and melty. Enjoy!